ABSTRACT
Backgrund: Chlamydia trachomatis is one of the most common identifiable infectious agents in neonatal conjunctivitis. It also causes pneumonitis, that is preceded by conjunctivitis in one third of cases. Aim: To asses the prevalence of Chlamydia trachomatis in newborns with conjunctivitis. Patients and methods: In 162 newborns, coming from 14 Primary Health Centers from Santiago de Chile, C. trachomatis was detected by indirect fluorescence and two polymerase chain reaction (PCR 1 and 2), wich amplified different sequences from the common endogenous plasmid. Those patients with positive indirect fluorescence and PCR 2 were definedas infected: Results: The prevalence of C. trachomatis was 8 percent, and the distribution of the positive cases was similar in the different Health Centers. Other isolates were: S. aureus (9.8 percent), S. pneumoniae (8 percent), S. viridans (6.2 percent) y H. influenzae (5.5 percent). Conclusions: The prevalence of C. trachomatis in neonatal conjunctivitis in Chile is similar to that of developed countries. Therefore, C. trachomatis should be considered in the election of antimicrobials for the treatment of neonatal conjunctivitis, to avoid ocular and respiratory complications
Subject(s)
Humans , Infant, Newborn , Male , Female , Chlamydia trachomatis/isolation & purification , Conjunctivitis, Inclusion/etiology , Infant, Newborn, Diseases/etiology , Chlamydia trachomatis/drug effects , Chlamydia trachomatis/pathogenicity , Polymerase Chain Reaction , Risk Factors , Anti-Bacterial Agents/therapeutic use , Conjunctivitis, Inclusion/diagnosis , Conjunctivitis, Inclusion/drug therapy , Infant, Newborn, Diseases/diagnosis , Socioeconomic Factors , Fluorescent Antibody Technique, DirectABSTRACT
De 1973 a 1990 se estudiaron en el Servicio de Microbiología e Inmunología del H.N.G.A.I. trescientos casos diagnosticados como conjuntivitis, de los cuales treinta correspondieron a "Conjuntivitis de inclusión". En estos pacientes se encontraron cuerpos de inclusión y los test de inmunofluorescencia dieron resultados positivos, oscilando sus títulos entre 1/64 y 1/1024.
Subject(s)
Humans , Male , Female , Conjunctivitis, Inclusion/diagnosis , Conjunctivitis, Inclusion/etiology , Conjunctivitis, Inclusion/microbiology , Chlamydia trachomatis/isolation & purification , Chlamydia trachomatis/pathogenicitySubject(s)
Humans , Male , Female , Child, Preschool , Adolescent , Adult , Middle Aged , Trachoma/classification , Trachoma/diagnosis , Trachoma/etiology , Conjunctival Diseases/diagnosis , Conjunctival Diseases/etiology , Conjunctivitis, Inclusion/complications , Conjunctivitis, Inclusion/diagnosis , Conjunctivitis, Inclusion/etiologyABSTRACT
Clamídias säo bactérias que, no homem, provocam: tracom ocular, tracoma genital, conjuntivite de inclusäo, linfogranuloma venéreo, síndrome de Reiter e a psitacose. É a maior causa de doença sexualmente transmitida, especialmente entre adolescentes e adultos jovens. No presente trabalho säo estudados, além de outros, os aspectos morfológicos, patogênicos e epidemiológicos